New drug cocktail aims to beat lymphoma without chemo

NCT ID NCT07496229

Recruiting now Disease control Sponsor: Dizal Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a combination of two drugs, GW5282 and golidocitinib, for people with T-cell lymphoma. The first part finds the safest dose; the second part compares the combo to standard chemotherapy. About 165 adults with newly diagnosed or relapsed disease will take part. The goal is to see if the combo works better and is safer than current treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: GW5282 combined with golidocitinib
What this could lead to: If successful, this could offer a new chemo-free combination therapy for T-cell lymphoma, potentially improving response rates and reducing side effects compared to standard treatment.
What could go wrong: This is an early phase 1/2 trial with a small number of participants, so results may not apply broadly. The combination may cause unexpected side effects or fail to show better outcomes than standard chemo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERIPHERAL T-CELL LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

mature T-cell and NK-cell non-Hodgkin lymphoma T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

T-CELL LYMPHOMAS

Contacts and locations

Locations

Chongqing Cancer Hospital
NOT_YET_RECRUITING

Chongqing, Chongqing Municipality, China
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, China
Fujian Cancer Hospital
NOT_YET_RECRUITING

Fuzhou, Fujian, China
Guangxi Medical University Cancer Hospital
NOT_YET_RECRUITING

Nanning, Guangxi, China
Henan Cancer Hospital
NOT_YET_RECRUITING

Zhengzhou, China
Henan Provincial People's Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, China
Nanjing Drum Tower Hospital
NOT_YET_RECRUITING

Nanjing, Jiangsu, China
Shanxi Provincial Cancer Hospital
NOT_YET_RECRUITING

Taiyuan, China
Taizhou Hospital of Zhejiang Province
NOT_YET_RECRUITING

Taizhou, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITING

Wenzhou, Zhejiang, China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITING

Wuhan, Hubei, China
West China Hospital of Sichuan University
NOT_YET_RECRUITING

Chengdu, Sichuan, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.