Could a gut Bug's protein help control blood sugar?
NCT ID NCT06923839
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether a peptide made by a common gut bacterium, RUCILP, can affect blood sugar and hunger-related hormones in 15 healthy men. Participants receive either the peptide or a placebo through a tube in the small intestine. The study aims to see if RUCILP changes levels of key hormones like GLP-1 and insulin, which are important for metabolism.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RUCILP (a gut bacterial peptide)
What this could lead to
If it works, this could point toward a new way to manage blood sugar or appetite using a natural gut molecule.
What could go wrong
This is a very early Phase 1 trial with only 15 healthy men. It tests short-term effects, not long-term safety or benefit. Results may not apply to people with health conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Gentofte Hospital
Hellerup, 2900, Denmark