Scientists investigate gut Microbiome's role in lung cancer therapy

NCT ID NCT06221800

First seen Feb 05, 2026 · Last updated Jun 23, 2026 · Updated 23 times

Summary

This pilot study is collecting stool and saliva samples from 82 people with advanced non-small cell lung cancer to see if the diversity of their gut microbiome is linked to how well their treatment works and what side effects they experience. The goal is to better understand the relationship between gut bacteria and cancer therapy outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Chao Family Comprehensive Cancer Center University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal how gut bacteria influence lung cancer treatment outcomes, potentially guiding future personalized therapies.

What could go wrong

This is a small pilot study (82 participants) focused on observation, not treatment. It may not produce clear or generalizable results.

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.