Leaky gut in treated HIV: scientists probe why immune repair fails

NCT ID NCT02906137

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study investigates why the gut immune barrier remains damaged in people with HIV even after successful antiretroviral therapy. Researchers collected blood and intestinal biopsies from 80 participants to measure immune cells and inflammation. The goal is to understand why the gut doesn't fully recover, which could help reduce long-term health problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new ways to help the gut immune system recover in people living with HIV, potentially reducing long-term inflammation.

What could go wrong

This is an observational study, not a treatment trial. It aims to understand the problem, not test a solution. Results may not lead directly to new therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Purpan - Service de Médecine Interne

    Toulouse, 31059, France

  • Hôpital Purpan - Service des maladies Infectieuses

    Toulouse, 31059, France