Gut bugs fight back against Drug-Resistant skin cancer

NCT ID NCT06540391

Summary

This early-stage trial is testing whether adding a specific mix of gut bacteria (MB097) to a standard immunotherapy drug (pembrolizumab) can help patients with advanced melanoma whose cancer has stopped responding to similar treatments. The main goal is to see if this combination is safe and if the bacteria successfully colonize the gut. Researchers will also look for early signs that the treatment might help control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP-HM - Hopital de la Timone

    Marseille, France

  • Addenbrooke's Hospital

    Cambridge, United Kingdom

  • Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

  • CHU de Lille - Hopital Claude Huriez

    Lille, France

  • Centre Georges Francois Leclerc

    Dijon, France

  • Centre Leon Berard

    Lyon, France

  • Consorcio Hospital General Universitario de Valencia

    Valencia, Spain

  • Freeman Hospital

    Newcastle, United Kingdom

  • HCL Centre Hospitalier Lyon Sud

    Pierre-Bénite, France

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, Spain

  • Istituto Clinico Humanitas

    Rozzano, Italy

  • Istituto Europeo di Oncologia

    Milan, Italy

  • Istituto Nazionale Tumori IRCCS Fondazione G. Pascale

    Naples, Italy

  • Royal Marsden Hospital - Surrey

    Sutton, United Kingdom

  • South Texas Accelerated Research Therapeutics (START) Madrid - CIOCC

    Madrid, Spain

  • Sussex Cancer Centre

    Brighton, United Kingdom

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • The Royal Marsden NHS Foundation Trust

    London, United Kingdom

Conditions

Explore the condition pages connected to this study.