New combo therapy offers hope for patients with stubborn IBD

NCT ID NCT07487311

First seen Apr 05, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tests whether combining two drugs—guselkumab and a JAK inhibitor (like upadacitinib or tofacitinib)—can help people with inflammatory bowel disease (IBD) that hasn't responded to standard treatments. About 80 participants aged 14-80 with moderate to severe IBD will receive the combination and be followed for up to 52 weeks to see if symptoms improve and the gut lining heals. The goal is to offer a new option for those with limited choices.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center of Inflammatory Bowel Disease, Department of Gastroenterology, the Second Affiliated Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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