New hope for kids with severe bowel disease

NCT ID NCT06260163

Ongoing Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing a medicine called guselkumab in children and teenagers with moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. It aims to see if the drug can help control the disease, reduce symptoms like abdominal pain and bleeding, and improve gut healing over 56 weeks. The trial involves about 112 young participants who haven't responded well to other treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

AOU Meyer

Florence, 50139, Italy
AOU Policlinico Umberto I

Roma, 00161, Italy
APHP Hopital Robert Debre

Paris, 75019, France
ASST Papa Giovanni XXIII Bergamo

Bergamo, 24127, Italy
Aarhus Universitetshospital

Aarhus N, 8200, Denmark
Akershus Universitetssykehus

Lørenskog, 1478, Norway
Ankara University Medical Faculty

Ankara, 6620, Turkey (Türkiye)
Azienda USL di Bologna - Ospedale Maggiore

Bologna, 40133, Italy
CHRU Lille

Lille, 59037, France
CHU Charleroi Chimay

Charleroi, 6042, Belgium
CHU Toulouse

Toulouse, 31059, France
Capital Center For Children's health Capital Medical University

Beijing, 100020, China
Casa Sollievo della Sofferenza

San Giovanni Rotondo, 71013, Italy
Changzhou No 2 Peoples Hospital

Changzhou, 213004, China
Children's Hospital Oakland

Oakland, California, 94609, United States
Copernicus Podmiot Leczniczy Sp. z o.o

Gdansk, 80 803, Poland
Corporacio Sanitari Parc Tauli

Sabadell, 08028, Spain
Gazi University Medical Faculty

Ankara, 06560, Turkey (Türkiye)
Henan Children's Hospital, Zhengzhou Children's Hospital

Zhengzhou, 450052, China
Hopital Francois Mitterand

Dijon, 21000, France
Hosp. Infantil Univ. Nino Jesus

Madrid, 28009, Spain
Hosp. Univ. I Politecni La Fe

Valencia, 46026, Spain
Hospices Civils de Lyon - Groupement Hospitalier Est - Hopital Femme Mere Enfant

Bron, 69677, France
Hvidovre Hospital

Hvidovre, 2650, Denmark
IRCCS Materno Infantile Burlo Garofolo

Trieste, 34137, Italy
IRCCS Ospedale Pediatrico Bambino Gesu

Roma, 00165, Italy
Instytut Pomnik Centrum Zdrowia Dziecka

Warsaw, 04 730, Poland
Istanbul University Cerrahpasa Medical Faculty

Istanbul, 34098, Turkey (Türkiye)
Japanese Red Cross Kumamoto Hospital

Kumamoto, 861 8520, Japan
Kanazawa University Hospital

Kanazawa, 920 8641, Japan
Kobe University Hospital

Kobe, 650 0017, Japan
Korczowski Bartosz Gabinet Lekarski

Rzeszów, 35-302, Poland
Marmara University Pendik Training Hospital

Istanbul, 34899, Turkey (Türkiye)
Mater Hospital Brisbane Inflammatory Bowel Diseases

South Brisbane, 4101, Australia
Medical Network Spolka z o.o. WIP Warsaw IBD Point Profesor Kierkus

Warsaw, 04 501, Poland
NYU Langone Health

Lake Success, New York, 11042, United States
National Center for Child Health and Development

Setagaya Ku, 157 8535, Japan
Osaka Medical and Pharmaceutical University Hospital

Takatsuki, 569-8686, Japan
Oslo University Hospital

Oslo, 0450, Norway
Ospedale S. Spirito, Azienda Sanitaria Pescara

Pescara, 65124, Italy
Peking University Third Hospital

Beijing, 100191, China
Riley Hospital for Children

Indianapolis, Indiana, 46202, United States
Ruijin Hospital Shanghai Jiao Tong University

Shanghai, 200025, China
Saga University Hospital

Saga, 849-8501, Japan
Saiseikai Yokohamashi Tobu Hospital

Yokohama, 230-8765, Japan
Shengjing Hospital Of China Medical University

Shenyang, 110004, China
Shinshu University Hospital

Matsumoto, 390 8621, Japan
Sir Run Run Shaw Hospital Zhejiang University School of Medicine

Hangzhou, 310016, China
St. Olavs Hospital

Trondheim, 7030, Norway
The Children's Hospital at Westmead

Westmead, 2145, Australia
The Childrens Hospital Zhejiang University School Of Medicine

Hangzhou, 310005, China
The Kids Research Institute Australia on behalf of the Centre for Child Health Research

Nedlands, 6009, Australia
Tokyo Medical University Hospital

Shinjuku, 160 0023, Japan
Tokyo Metropolitan Children's Medical Center

Fuchū, 183 8561, Japan
UZ Brussel

Jette, 1090, Belgium
UZ Gent

Ghent, 9000, Belgium
UZ Leuven

Leuven, 3000, Belgium
Uls Santa Maria - Hosp. Santa Maria

Lisbon, 1649-035, Portugal
Uls Santo Antonio - Cmin

Porto, 4050-651, Portugal
Uls Sao Joao - Hosp. Sao Joao

Porto, 4200 319, Portugal
Universitetssykehuset Nord-Norge HF

Tromsø, 9030, Norway

Conditions

Explore the condition pages connected to this study.

COLITIS, ULCERATIVE