Can a new drug heal Crohn's from the inside out?

NCT ID NCT06408935

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 25 times

Summary

This study tests a drug called guselkumab in 120 adults with Crohn's disease. The goal is to see if it can heal all layers of the digestive tract, measured by MRI scans at 48 weeks. Participants receive the drug and are monitored for healing and symptom changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • APHP - Hopital Bichat - Claude Bernard

    Paris, 75018, France

  • ASL Toscana Nord Ovest PO Valdera Ospedale Lotti

    Pontedera Pisa, 56025, Italy

  • ASST Fatebenefratelli Sacco

    Milan, 20121, Italy

  • AZ Maria Middelares

    Ghent, 9000, Belgium

  • Aphm - Hopital Nord

    Marseille, 13915, France

  • Asst Rhodense - Ospedale Di Rho

    Rho, 20017, Italy

  • Azienda Ospedaliera Policlinico S. Orsola-Malpighi

    Bologna, 40138, Italy

  • BSF Studiengesellschaft

    Halle, 06108, Germany

  • CHRU de Lille Hopital Claude Huriez

    Lille, 59000, France

  • CHU Amiens Picardie

    Amiens, 80054, France

  • CHU de Clermont Ferrand

    Clermont-Ferrand, 63000, France

  • CHU de Liege

    Liège, 4000, Belgium

  • CHU de Nantes hotel Dieu

    Nantes, 44000, France

  • Center for Colitis and Crohns Disease University of California

    San Francisco, California, 94115, United States

  • Centrum Medyczne Medyk

    Rzeszów, 35-326, Poland

  • Centrum Medyczne Oporow

    Wroclaw, 52-416, Poland

  • Chang-Hua Christian Hospital

    Changhua, 500, Taiwan

  • Charite Universitaetsmedizin Berlin

    Berlin, 10117, Germany

  • Cliged

    Macaé, 27910-020, Brazil

  • Cliniq s.r.o.

    Bratislava, 811 09, Slovakia

  • Complejo Hosp Univ. de Ferrol

    Ferrol, 15405, Spain

  • Concord Repatriation General Hospital

    Concord, 2139, Australia

  • ENDOMED s.r.o

    Košice, 040 13, Slovakia

  • ETG Zamosc

    Zamość, 22-400, Poland

  • EuroMediCare Szpital Specjalistyczny z Przychodnia

    Wroclaw, 54 144, Poland

  • FNsP F.D.R. Banska Bystrica

    Banská Bystrica, 975 17, Slovakia

  • Far Eastern Memorial Hospital

    New Taipei City, 22060, Taiwan

  • Fiona Stanley Hospital

    Murdoch, 6150, Australia

  • Fondazione Policlinico Tor Vergata

    Roma, 00133, Italy

  • Fondazione Policlinico Universitario A Gemelli IRCCS

    Roma, 00168, Italy

  • Foothills Hospital

    Calgary, Alberta, T2N 4Z6, Canada

  • GASTRO I. s.r.o.

    Prešov, 080 01, Slovakia

  • GASTROMED Sp. z o.o.

    Torun, 87 100, Poland

  • Galilee Medical Center

    Nahariya, 2210001, Israel

  • Hadassah Medical Organization

    Jerusalem, 91200, Israel

  • Hepato-gastroenterologie HK, s.r.o.

    Hradec Králové, 500 12, Czechia

  • Hopital du Sacre-Coeur de Montreal

    Montreal, Quebec, H4J 1C5, Canada

  • Hosp Reina Sofia

    Córdoba, 14004, Spain

  • Hosp. Alvaro Cunqueiro

    Vigo, 36213, Spain

  • Hosp. Clinico Univ. de Valencia

    Valencia, 46010, Spain

  • Hosp. Gral. Univ. Dr. Balmis

    Alicante, 3010, Spain

  • Hosp. Univ. Pta. de Hierro Majadahonda

    Madrid, 28222, Spain

  • Hosp. Univ. de La Paz

    Ferrol, 15405, Spain

  • Hosp. Univ. de La Princesa

    Madrid, 28006, Spain

  • INTEGRAL Pesquisa e Ensino

    Votuporanga, 15501-405, Brazil

  • IRCCS Humanitas Rozzano-IBD Center Malattie Infiammatorie Croniche Intestinali

    Rozzano, 20089, Italy

  • IRCCS Ospedale Casa Sollievo della Sofferenza

    San Giovanni Rotondo, 71013, Italy

  • IRCCS Ospedale San Raffaele

    Milan, 20132, Italy

  • ISCARE a.s.

    Prague, 19000, Czechia

  • Instituto Mederi de Pesquisa e Saude

    Passo Fundo, 99010-120, Brazil

  • KM Management spol. s r.o.

    Nitra, 949 01, Slovakia

  • Klinikum Augsburg

    Augsburg, D-86158, Germany

  • MVZ Portal 10

    Münster, 48155, Germany

  • Mater Hospital Brisbane

    South Brisbane, 4101, Australia

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Medizinisches Versorgungszentrum (MVZ) Dachau

    Dachau, 85221, Germany

  • Melita Medical Sp. z o.o.

    Wroclaw, 50 449, Poland

  • NPCRS Nucleo de Pesquisa Clinica do Rio Grande do Sul

    Porto Alegre, 90430001, Brazil

  • NZOZ Centrum Medyczne KERmed

    Bydgoszcz, 85 231, Poland

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Nemocnice Ceske Budejovice a s

    České Budějovice, 370 87, Czechia

  • Northern Hospital

    Melbourne, 3076, Australia

  • Praxis Fur Gastroenteroligie

    Berlin, 10825, Germany

  • Rabin Medical Center

    Petah Tikva, 49100, Israel

  • Rambam Medical Center

    Haifa, 31096, Israel

  • Siloah St Trudpert Klinikum

    Pforzheim, 75179, Germany

  • Staedtisches Klinikum Lueneburg

    Lüneburg, 21339, Germany

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, 6423906, Israel

  • The Chaim Sheba Medical Center

    Ramat Gan, 5265601, Israel

  • The Edith Wolfson Medical Center

    Holon, 58100, Israel

  • The Queen Elizabeth Hospital

    Adelaide, 5011, Australia

  • The University of Chicago Medical Center (UCMC)

    Chicago, Illinois, 60637, United States

  • Universita Campus Bio-Medico di Roma

    Roma, 00128, Italy

  • Universita Di Napoli Federico Ii

    Naples, 80131, Italy

  • Universitaetsklinikum Ulm

    Ulm, 89081, Germany

  • Universitatsklinikum Frankfurt/ Medizinische Klinik 1

    Frankfurt, 60590, Germany

  • Universitatsklinikum Schleswig Holstein

    Kiel, 24105, Germany

  • Universitatsmedizin Gottingen

    Göttingen, 37075, Germany

  • Vitaz

    Sint-Niklaas, Belgium

  • WIP Warsaw IBD Point Profesor Kierkus

    Warsaw, 00-728, Poland

  • Washington University School Of Medicine

    St Louis, Missouri, 63110, United States

  • Western University & London Health Sciences Centre

    London, Ontario, N6A 5A5, Canada

Conditions

Explore the condition pages connected to this study.