New hope for Crohn's patients: drug switch may tame stubborn gut inflammation

NCT ID NCT07310095

Recruiting now Disease control Sponsor: Xian-Janssen Pharmaceutical Ltd. Source: ClinicalTrials.gov ↗

First seen Jan 06, 2026 · Last updated May 08, 2026 · Updated 14 times

Summary

This study tests whether guselkumab can help people with Crohn's disease whose current treatment (ustekinumab) has stopped working. About 78 Chinese adults with active Crohn's will receive guselkumab and be followed for 48 weeks. The main goal is to see if their symptoms improve enough to achieve remission, meaning less pain and fewer bowel issues.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Ruijin Hospital
RECRUITING

Shanghai, 200031, China
Sir Run Run Shaw Hospital Zhejiang University School of Medicine
RECRUITING

Hangzhou, 310018, China
The First Affiliated Hospital Sun Yat sen University
RECRUITING

Guangzhou, 510060, China
The First Affiliated Hospital of Anhui Medical University
RECRUITING

Hefei, 230022, China
The Sixth Affiliated Hospital Sun Yat sen University
RECRUITING

Guangzhou, 510655, China

Conditions

Explore the condition pages connected to this study.

CROHN DISEASE