New 3D-Printed implant may fix gummy smiles without major surgery

NCT ID NCT06017791

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a custom 3D-printed PEEK shell placed under the gum in the upper jaw to reduce excessive gum display (gummy smile) in 10 patients. The shell was inserted through small incisions using a tunnel technique. The goal was to see if it could decrease the amount of gum showing when smiling, while also measuring pain, lip movement, and patient satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
3D-printed PEEK shell placed via tunnel technique
What this could lead to
If successful, this could offer a new, minimally invasive option to reduce a gummy smile without major surgery.
What could go wrong
This is a very small case series (10 people) with no control group, so results may not apply to everyone. Long-term safety and effectiveness are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Started

Nov 2023

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with excess gingival display 2.5mm or more * Patients with an exaggerated subnasal concavity * Decreased/normal value of SNA ( angle between sella, nation, A point) in cephalometric measurement * Decreased/normal cephalometric measurement of A to N-perpendicular (perpendicular from N on FHP) * Decreased/normal value in cephalometric measurement of the convexity at point A (linear measurement from point A to facial plane) * Decreased/normal value of Ricketts Esthetic plane in cephalometric measurement * Decreased/normal value of Holdaway H-angle in cephalometric measurement * Nasolabial angle range from 100° to 120° * Patients 20-60 years old * Medically free * Compliant patient that agrees to the follow up period Exclusion Criteria: * Pregnant and lactating females * Smokers * Diabetics * Patients with parafunctional habits that may affect the outcome of the procedure * Medically compromised patients

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Farah Mamdouh

    Cairo, 11835, Egypt

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