Can Platelet-Rich fibrin or laser therapy boost gummy smile surgery results?

NCT ID NCT07532161

First seen Apr 23, 2026 · Last updated Jun 19, 2026 · Updated 12 times

Summary

This study tests whether adding liquid platelet-rich fibrin or low-level laser therapy to standard lip repositioning surgery can speed healing, reduce pain and swelling, and prevent the gummy smile from returning. Twenty-two adults with a gummy smile due to a hyperactive upper lip will be randomly assigned to one of the two treatments. The goal is to see which approach leads to better wound healing and longer-lasting cosmetic results.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GUMMY SMILE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Dentistry, Damascus university , Syria.

    RECRUITING

    Damascus, Rif-dimashq Governorate, Syria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liquid platelet-rich fibrin and low-level laser therapy

What this could lead to

If it works, this could point toward a better way to heal and maintain results after gummy smile surgery, reducing pain and swelling.

What could go wrong

This is a very small, early-phase trial with only 22 participants, so results may not apply to everyone. The treatments are adjunctive, not a cure, and relapse may still occur.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.