Can Platelet-Rich fibrin or laser therapy boost gummy smile surgery results?

NCT ID NCT07532161

Recruiting now Symptom relief Sponsor: Damascus University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding liquid platelet-rich fibrin or low-level laser therapy to standard lip repositioning surgery can speed healing, reduce pain and swelling, and prevent the gummy smile from returning. Twenty-two adults with a gummy smile due to a hyperactive upper lip will be randomly assigned to one of the two treatments. The goal is to see which approach leads to better wound healing and longer-lasting cosmetic results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: liquid platelet-rich fibrin and low-level laser therapy
What this could lead to: If it works, this could point toward a better way to heal and maintain results after gummy smile surgery, reducing pain and swelling.
What could go wrong: This is a very small, early-phase trial with only 22 participants, so results may not apply to everyone. The treatments are adjunctive, not a cure, and relapse may still occur.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GUMMY SMILE

Contacts and locations

Locations

Faculty of Dentistry, Damascus university , Syria.
RECRUITING

Damascus, Rif-dimashq Governorate, Syria

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