Could a Blood-Derived gel improve gum recession surgery?
NCT ID NCT07717398
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This study tests whether a combination of injectable platelet-rich fibrin (I-PRF) and a collagen membrane can improve coverage of receding gums. The trial includes adults with Miller Class II gum recession, a condition where the gum margin has moved away from the tooth. Participants receive either the new I-PRF plus collagen treatment or a standard gum graft surgery. Researchers measure gum thickness, recession depth, and healing over time to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- injectable platelet-rich fibrin (I-PRF) combined with a collagen membrane
- What this could lead to
- If successful, this approach could offer a less invasive, more effective way to cover exposed tooth roots and improve gum healing.
- What could go wrong
- This is a small, early-stage trial with only 20 participants, so results may not apply to everyone. The treatment may not outperform the standard graft procedure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faculty of dentistry ,Tanta university
Tanta, Gharbia Governorate, Egypt