Gum graft showdown: own tissue vs. collagen matrices for implant aesthetics
NCT ID NCT07605286
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to thicken gums around dental implants: using the patient's own tissue or a collagen matrix. 84 adults received one of four treatments, and researchers measured gum thickness, color, and healing over 6 months. The goal was to find which method works better and is safer for improving smile appearance.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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84 people
The number who actually took part.
- Started
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Oct 2021
- Finished
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Oct 2024
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 21 and 75 years * Requirement for single dental implant placement in the mandibular molar region (replacing no more than one tooth) * Need for soft tissue augmentation to achieve peri-implant mucosal thickness ≥2 mm * Signed voluntary informed consent for treatment and research participation * Ability and willingness to attend all scheduled follow-up examinations for 12 months post-surgery * Adequate oral hygiene and commitment to maintain it throughout the study period Exclusion Criteria: * Presence of systemic diseases in a decompensated stage (e.g., uncontrolled diabetes, severe cardiovascular disease) * Current or prior use of immunosuppressants, bisphosphonates, or high-dose corticosteroids * History of cancer, radiation therapy, or chemotherapy within 5 years prior to enrollment * Need for concurrent bone grafting or immediate implant placement following tooth extraction * Active periodontal disease or untreated oral infections at the time of surgery * Heavy smoking (\>10 cigarettes/day) or inability to abstain from smoking during the healing period * Pregnancy or lactation * Known allergy to collagen, porcine/bovine products, or materials used in the study (sutures, anesthetics) * Participation in another clinical trial within 30 days prior to enrollment * Refusal to participate in any stage of the study or inability to comply with study procedures * Psychological or social conditions that, in the investigator's judgment, may compromise protocol adherence or data reliability
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Central Research Institute of Dental and Maxillofacial Surgery
Moscow, 119021, Russia
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