Prenatal genome sequencing: helpful or just worrying?
NCT ID NCT07610590
First seen Jun 26, 2026 · Last updated Jul 16, 2026 · Updated 3 times
Summary
This study looks at whether genome sequencing (reading nearly all of a baby's genes) should be used more routinely during pregnancy, even when ultrasounds look normal. Researchers will compare this test with current standard prenatal testing in over 1,000 families to see if it finds more genetic conditions and how parents use that information. The goal is to understand if genome sequencing can be offered in a way that is helpful, responsible, and supportive for families.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Genome sequencing (GS)
- What this could lead to
- If successful, this could show that genome sequencing is a helpful and responsible addition to routine prenatal care, giving families more information about their baby's health.
- What could go wrong
- This is an observational study, not a treatment trial. It may find genetic variants of uncertain significance, which can cause anxiety without clear answers. Results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Boston Childrens Hospital
ACTIVE_NOT_RECRUITINGBoston, Massachusetts, 02115, United States
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Columbia University Irving Medical Center (CUIMC)
RECRUITINGNew York, New York, 10032, United States
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New York Genome Center
ACTIVE_NOT_RECRUITINGNew York, New York, 10013, United States
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