Can a 3D-Printed guide make dental cyst surgery more precise?
NCT ID NCT07724964
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial tests whether a 3D-printed surgical guide can improve the accuracy and outcomes of apicoectomy—a procedure to remove the tip of a tooth root and a nearby cyst—in adults with periapical cysts in premolar teeth. Forty-two participants will undergo guided surgery using cone-beam CT and digital planning, with follow-up over six months to assess healing and success rates. The goal is to see if this technology reduces bone removal and damage to nearby structures compared to traditional methods.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- guided apicoectomy with retrograde mineral trioxide aggregate filling
- What this could lead to
- If successful, this guided surgical technique could offer a more precise, less invasive option for treating periapical cysts, potentially reducing complications and improving recovery.
- What could go wrong
- This is a small, single-arm study with only 42 participants and no comparison group, so results may not be generalizable. Risks include infection, nerve damage, or failure of the cyst to heal.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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42 people
The number who actually took part.
- Started
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May 2025
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults diagnosed with a periapical cyst involving a premolar tooth. * Diagnosis confirmed by clinical examination and CBCT. * Histopathological confirmation of periapical cyst after surgery. * Root canal treatment completed with acceptable obturation quality. * Tooth considered restorable. * No previous apicoectomy on the study tooth. * Able to provide written informed consent. Exclusion Criteria: * Uncontrolled systemic diseases. * Coagulation disorders. * Uncontrolled diabetes mellitus. * Active malignancy receiving radiotherapy. * Severe cardiovascular disease contraindicating surgery. * Vertical root fracture. * Grade IV tooth mobility. * Allergy to local anesthetics or study materials. * Previous surgery for recurrent periapical cyst at the study site. * Inability to comply with follow-up schedule.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Orthodontics, Ho Chi Minh City Dental Hospital
Ho Chi Minh City, Vietnam
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