Heart Patients' genes may guide safer, more effective clot prevention

NCT ID NCT03783351

First seen Jan 08, 2026 · Last updated May 13, 2026 · Updated 19 times

Summary

This study looked at whether using a genetic test to choose blood thinners can reduce heart attacks, strokes, and death in people who have had a heart stent placed. About 4,000 adults with stable angina or acute coronary syndrome were given either clopidogrel or ticagrelor based on their CYP2C19 gene type. The goal was to see if personalized medicine can improve outcomes without increasing bleeding risks.

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Contacts and locations

Locations

  • Beijing Anzhen Hospital

    Beijing, Beijing Municipality, 100029, China

  • Beijing Chaoyang Hospital

    Beijing, Beijing Municipality, 100000, China

  • Beijing Friendship Hospital

    Beijing, Beijing Municipality, 100050, China

  • Beijing LuHe Hospital

    Beijing, Beijing Municipality, 101199, China

  • Beijing Tong Ren Hospital

    Beijing, Beijing Municipality, 100730, China

  • Beijing Tsinghua Changgung Hospital

    Beijing, Beijing Municipality, 102218, China

  • China-Japan Friendship Hospital

    Beijing, Beijing Municipality, China

  • Fuwai Hospital Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100037, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100032, China

Conditions

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