Patient's own immune cells take on head and neck cancer in new trial

NCT ID NCT06190275

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new treatment called GT201, made from a patient's own tumor-fighting immune cells (TILs), combined with a PD-1 inhibitor drug. The goal is to see if this combination is safe and tolerable for 32 adults with advanced head and neck cancer that has returned or spread. The trial has two phases: first finding the right dose, then expanding to see how well it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GT201 (tumor-infiltrating lymphocytes) combined with a PD-1 inhibitor

What this could lead to

If successful, this could point toward a new treatment option for advanced head and neck cancer that uses the patient's own immune cells to fight tumors.

What could go wrong

This is a very early, small trial (32 people) focused on safety, not proof of effectiveness. The combination therapy may cause severe side effects, and it's unknown if it will shrink tumors or improve survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Ninth People's Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact