Gene therapy aims to restore sight in rare inherited blindness

NCT ID NCT07303296

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a gene therapy called GS010 for people with Leber hereditary optic neuropathy (LHON), a genetic condition that causes rapid vision loss. Researchers will give the treatment as an injection into the eye at two different doses to see if it improves vision and mitochondrial activity. The trial involves 14 participants aged 15 or older who have vision loss in both eyes due to a specific ND4 gene mutation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Hopital national des quinze-vingts

    RECRUITING

    Paris, 75012, France

    Contact Email: •••••@•••••

    Contact