New drug aims to tame overactive thyroid in Graves' disease

NCT ID NCT07018323

Recruiting now Disease control Sponsor: Immunovant Sciences GmbH Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 11, 2026 · Updated 28 times

Summary

This study tests a new medicine called IMVT-1402 for adults with Graves' disease whose thyroid is still overactive despite current treatments. About 210 participants will receive either the drug or a placebo to see if it can bring thyroid levels back to normal and allow them to stop other thyroid medications. The goal is better disease control, not a cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

Site Nnumber - 3003
RECRUITING

Wroclaw, 50-367, Poland
Site Number - 1000
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Miami, Florida, 33143, United States
Site Number - 1001
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Morehead City, North Carolina, 27577, United States
Site Number - 1002
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El Paso, Texas, 79935, United States
Site Number - 1003
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Fort Worth, Texas, 76132, United States
Site Number - 1004
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Kansas City, Missouri, 64110, United States
Site Number - 1007
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Oklahoma City, Oklahoma, 73134, United States
Site Number - 1008
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Hialeah, Florida, 33016, United States
Site Number - 1009
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New York, New York, 10022, United States
Site Number - 1010
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Chapel Hill, North Carolina, 27514, United States
Site Number - 1011
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San Antonio, Texas, 78231, United States
Site Number - 1012
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Reno, Nevada, 89511, United States
Site Number - 1013
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Aurora, Colorado, 80045, United States
Site Number - 1015
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Tucson, Arizona, 85710, United States
Site Number - 1016
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Norfolk, Virginia, 23510, United States
Site Number - 1017
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Memphis, Tennessee, 38119, United States
Site Number - 1018
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Williamsville, New York, 14221, United States
Site Number - 1019
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St Louis, Missouri, 63110, United States
Site Number - 1020
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Columbus, Georgia, 31904, United States
Site Number - 1021
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Irving, Texas, 75039, United States
Site Number - 1022
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Topeka, Kansas, 66606, United States
Site Number - 1024
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Doral, Florida, 33166, United States
Site Number - 1025
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McKinney, Texas, 75069, United States
Site Number - 1026
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Hickory, North Carolina, 28601, United States
Site Number - 1027
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New Hyde Park, New York, 11434, United States
Site Number - 1028
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Houston, Texas, 77054, United States
Site Number - 1029
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Dallas, Texas, 75224, United States
Site Number - 1030
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Louisville, Kentucky, 40202, United States
Site Number - 1031
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Houston, Texas, 77030, United States
Site Number - 1032
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Long Island City, New York, 11106, United States
Site Number - 1033
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Jefferson City, Missouri, 65109, United States
Site Number - 1034
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Raleigh, North Carolina, 27612, United States
Site Number - 2003
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Rotterdam, South Holland, 3045 PM, Netherlands
Site Number - 2200
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Rotterdam, South Holland, 3079 DZ, Netherlands
Site Number - 2201
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Rotterdam, South Holland, 3083 AN, Netherlands
Site Number - 2202
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Zwijndrecht, South Holland, 3318 AT, Netherlands
Site Number - 3000
RECRUITING

Lublin, 20-607, Poland
Site Number - 3001
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Szczecin, West Pomeranian Voivodeship, 71-252, Poland
Site Number - 3002
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Bydgoszcz, 85-605, Poland
Site Number - 3004
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Bialystok, Podlaskie Voivodeship, 15-276, Poland
Site Number - 3005
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Olsztyn, 10-117, Poland
Site Number - 3006
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Poznan, 60-693, Poland
Site Number - 3007
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Kielce, 25-734, Poland
Site Number - 3008
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Warsaw, 02-482, Poland
Site Number - 3009
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Opole, 45-301, Poland
Site Number - 3010
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Chorzów, 41-516, Poland
Site Number - 3200
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Prague, 181 00, Czechia
Site Number - 3201
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Prague, 149 00, Czechia
Site Number - 3202
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Prague, 190 14, Czechia
Site Number - 3203
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Náchod, 547 01, Czechia
Site Number - 3300
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Wellington, 6242, New Zealand
Site Number - 3301
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Auckland, 2025, New Zealand
Site Number - 3900
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Athens, 115 27, Greece
Site Number - 3901
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Athens, 115 28, Greece
Site Number - 3902
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Athens, 106 76, Greece
Site Number - 4005
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Minokamo, Gifu, 505-8510, Japan
Site Number - 4006
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Kyoto, 612-8555, Japan
Site Number - 4200
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Petah Tikva, 4941492, Israel
Site Number - 4201
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Jerusalem, 9103102, Israel
Site Number - 4202
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Ramat Gan, Central District, 5265601, Israel
Site Number - 4203
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Haifa, Haifa District, 3109601, Israel
Site Number - 4204
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Jerusalem, 9112001, Israel
Site Number - 4205
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Haifa, Haifa District, 3104802, Israel
Site Number - 4206
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Tzfat, Northern District, 1311001, Israel
Site Number - 4207
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Tel Aviv, 6423906, Israel
Site Number - 4208
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Rehovot, 7661041, Israel
Site Number - 4209
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Nahariya, Northern District, 2210001, Israel
Site Number - 4210
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Kfar Saba, 4428164, Israel
Site Number - 4211
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Beersheba, Southern District, 8410101, Israel
Site Number - 4500
RECRUITING

Daegu, 42415, South Korea
Site Number - 4501
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Seoul, 02841, South Korea
Site Number - 4503
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Goyang, 410-77, South Korea
Site Number - 4504
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Guri-si, 11923, South Korea
Site Number - 4505
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Seoul, 05278, South Korea
Site Number - 4506
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Seoul, 03181, South Korea
Site Number - 4600
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Ogre, LV-5001, Latvia
Site Number - 4601
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Ventspils, LV-3601, Latvia
Site Number - 4602
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Riga, LV-1006, Latvia
Site Number - 4603
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Riga, LV-1050, Latvia
Site Number - 4604
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Sigulda, LV-2150, Latvia
Site Number - 5100
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Southport, Queensland, 4222, Australia
Site Number - 5101
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Brisbane, Queensland, 4101, Australia
Site Number - 5102
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Box Hill, Victoria, 3128, Australia
Site Number - 5103
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Warrawong, New South Wales, 2502, Australia
Site Number - 5104
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Geelong, Victoria, 3220, Australia
Site Number - 5105
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Sydney, New South Wales, 2050, Australia
Site Number - 5107
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Douglas, Queensland, 4814, Australia
Site Number - 5108
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Perth, 6009, Australia
Site Number - 5109
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Saint Leonards, 2065, Australia
Site Number - 5110
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Parkville, Victoria, 3050, Australia
Site Number - 5500
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Campinas, São Paulo, 09060-870, Brazil
Site Number - 5505
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Santo André, São Paulo, 09060-870, Brazil
Site Number - 5508
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São Paulo, 01228-000, Brazil
Site Number - 5512
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Rio de Janeiro, 21941-913, Brazil
Site Number - 5600
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Yambol, 8600, Bulgaria
Site Number - 5601
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Sliven, 8800, Bulgaria
Site Number - 5602
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Varna, 9002, Bulgaria
Site Number - 5603
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Varna, 9020, Bulgaria
Site Number - 5604
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Sofia, 1233, Bulgaria
Site Number - 5606
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Plovdiv, 4001, Bulgaria
Site Number - 5607
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Plovdiv, 4002, Bulgaria
Site Number - 5608
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Sofia, 1680, Bulgaria
Site Number - 5609
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Sofia, 1431, Bulgaria
Site Number - 5610
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Sofia, Sofia-Grad, 1431, Bulgaria
Site Number - 5611
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Varna, 9020, Bulgaria
Site Number - 5612
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Smolyan, 4700, Bulgaria
Site Number - 5613
RECRUITING

Dobrich, 7002, Bulgaria
Site Number - 6001
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Rome, 135, Italy
Site Number - 6002
RECRUITING

Udine, 33100, Italy
Site Number - 6003
RECRUITING

Milan, 20132, Italy
Site Number - 6005
RECRUITING

Rozzano, Milan, 20089, Italy
Site Number - 6006
RECRUITING

Pavia, 27100, Italy
Site Number - 7001
RECRUITING

London, W2 1NY, United Kingdom
Site Number - 7006
RECRUITING

London, SE1 9RT, United Kingdom
Site Number - 7008
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Surrey, GU2 7XX, United Kingdom
Site Number - 7009
RECRUITING

Cornwell, TR1 3LJ, United Kingdom
Site Number - 7010
RECRUITING

Salford, M6 8HD, United Kingdom
Site Number - 8000
RECRUITING

Tbilisi, 0145, Georgia
Site Number - 8001
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Tbilisi, 0160, Georgia
Site Number - 8002
RECRUITING

Tbilisi, 0159, Georgia
Site Number - 8003
RECRUITING

Tbilisi, 0114, Georgia
Site Number - 8004
RECRUITING

Imereti, 4600, Georgia
Site Number - 8005
RECRUITING

Tbilisi, 0186, Georgia
Site Number -1014
RECRUITING

Concord, California, 94520, United States
Site Number -1023
RECRUITING

Irving, Texas, 75031, United States
Site Number- 5605
RECRUITING

Sofia, 1750, Bulgaria

Conditions

Explore the condition pages connected to this study.

GRAVES DISEASE