Healthy donors needed to boost Infection-Fighting cells for vulnerable patients
NCT ID NCT01553214
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to improve the collection of granulocytes (a type of white blood cell) from healthy volunteers. Donors receive filgrastim and dexamethasone to move these cells into the bloodstream, then donate via apheresis. Up to 1,000 donors aged 18-75 can donate up to 12 times per year. The goal is to build a reliable donor registry to meet patient needs at the NIH Clinical Center.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
filgrastim and dexamethasone
What this could lead to
If successful, this could create a reliable donor program to provide granulocyte transfusions for patients with weakened immune systems, helping them fight infections.
What could go wrong
This is a Phase 4 study focused on donor feasibility, not treatment outcomes. Long-term effects of repeated filgrastim and dexamethasone in donors are still being monitored.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••