Cure My Disease

Don't miss your cure!

 Log in / Sign up

Grandmothers' health may shape Grandchildren's risk of asthma and obesity

NCT ID NCT03633162

Knowledge-focused Sponsor: Guangzhou Women and Children's Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers in Guangzhou, China, are following 5,000 grandmothers, their daughters, and their grandchildren to understand how health traits pass across three generations. The study collects information on lifestyle, environment, and social support, along with blood and tissue samples. Scientists will look at genes and immune factors to see whether a grandmother's biology can influence her grandchildren's risk of conditions like asthma, eczema, and obesity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study finds links across generations, it could shape how doctors think about inherited risk for obesity, asthma, and immune problems, and might one day inform advice for grandmothers, mothers, and children.
What could go wrong
This is an observational study, so it can show patterns but cannot prove cause and effect. Findings from one city in China may not apply to other populations, and the long follow-up means results will take years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 5,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2018

Expected to finish

Dec 2038

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All maternal grandmothers of the children in the Born in Guangzhou Cohort Study (BIGCS) would be recruited.

Ages

36 to 100 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Maternal Grandmother' grandchildren delivered in Guangzhou Women and Children's Medical Center 2. Baseline information of maternal grandmother's daughter during pregnancy available Exclusion Criteria: 1. Significant cardiovascular abnormalities 2. Intelligent obstacle, intellectual disabilities or gawkish condition

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Childhood obesity are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

neurodevelopmental disorder Pediatric Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Childhood obesity Hereditary transmission Host and microbiome Immune development Neurodevelopment

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Guangzhou Women and Children's Medical Center

    RECRUITING

    Guangzhou, Guangdong, 510623, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.