New shot may offer easier gout treatment without need for IV

NCT ID NCT07388498

First seen Feb 05, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tests if a shot under the skin (subcutaneous) of pegloticase works as well as the standard IV infusion for people with uncontrolled gout. Both groups also take methotrexate weekly. The goal is to lower uric acid levels below 6 mg/dL for most of the sixth month. About 270 adults with hard-to-treat gout will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Accellacare Salisbury

    RECRUITING

    Salisbury, North Carolina, 28144, United States

  • Advanced Clinical Research

    RECRUITING

    Miami, Florida, 33156, United States

  • Altoona Center for Clinical Research

    RECRUITING

    Duncansville, Pennsylvania, 16635, United States

  • Articularis Healthcare Group Inc dba Low Country Rheumatology

    RECRUITING

    Summerville, South Carolina, 29486, United States

  • Be Well Clinical Studies

    RECRUITING

    Round Rock, Texas, 78681, United States

  • Buffalo Rheumatology and Medicine

    RECRUITING

    Orchard Park, New York, 14127, United States

  • Cape Fear Arthritis Care, PLLC

    RECRUITING

    Leland, North Carolina, 28451, United States

  • Caribbean Health Research Center

    RECRUITING

    San Juan, 00917, Puerto Rico

  • Carolina Research Center Inc

    RECRUITING

    Shelby, North Carolina, 28150, United States

  • Charter Research

    RECRUITING

    Chicago, Illinois, 60618, United States

  • ClinPro Research Solutions LLC

    RECRUITING

    Tampa, Florida, 33613, United States

  • Conquest Research - Winter Park

    RECRUITING

    Winter Park, Florida, 32789, United States

  • D and H National Research Centers

    RECRUITING

    Miami, Florida, 33155, United States

  • D and H Pompano Research Center

    RECRUITING

    Aventura, Florida, 33180, United States

  • D and H Tamarac Research Center

    RECRUITING

    Tamarac, Florida, 33321, United States

  • Decision Management International Research

    RECRUITING

    Pinellas Park, Florida, 33782, United States

  • Denver Arthritis Clinic PC

    RECRUITING

    Denver, Colorado, 80230, United States

  • Epic Clinical Research

    RECRUITING

    Lewisville, Texas, 75057, United States

  • Felicidad Medical Research

    RECRUITING

    Miami, Florida, 33184, United States

  • Flourish Research Ravenswood

    RECRUITING

    Chicago, Illinois, 60640, United States

  • GCP Clinical Research, LLC

    RECRUITING

    Tampa, Florida, 33609, United States

  • Greater Chicago Specialty Physicians

    RECRUITING

    Schaumburg, Illinois, 60195, United States

  • Homestead Associates In Research Inc

    RECRUITING

    Homestead, Florida, 33033, United States

  • Integral Rheumatology and Immunology Specialists

    RECRUITING

    Plantation, Florida, 33324, United States

  • Joint and Muscle Research Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Kur Research at Columbia Medical Practice

    RECRUITING

    Columbia, Maryland, 21045, United States

  • MD Medical Research

    RECRUITING

    Oxon Hill, Maryland, 20745, United States

  • New Generation of Medical Research

    RECRUITING

    Hialeah, Florida, 33016, United States

  • Overlake Arthritis and Osteoperosis Center

    RECRUITING

    Bellevue, Washington, 98004, United States

  • Paramount Medical Research and Consulting LLC

    RECRUITING

    Middleburg Heights, Ohio, 44130, United States

  • Pioneer Research Solutions Inc

    RECRUITING

    Houston, Texas, 77099, United States

  • Shelby Clinical Research

    RECRUITING

    Shelby, North Carolina, 28150, United States

  • Solace Clinical Research

    RECRUITING

    Tustin, California, 92780, United States

  • Spatium Urgent Care

    RECRUITING

    Marietta, Georgia, 30066, United States

  • Vista Clinical Research

    RECRUITING

    Newnan, Georgia, 30265, United States

  • Well Pharma Medical Research Corp

    RECRUITING

    Miami, Florida, 33143, United States

  • Willow Rheumatology and Wellness

    RECRUITING

    Willowbrook, Illinois, 60527, United States

Conditions

Explore the condition pages connected to this study.