New hope for seniors with migraine: nerve zaps without drugs?

NCT ID NCT07363083

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a minimally invasive nerve treatment called pulsed radiofrequency (PRF) for chronic migraine in people aged 65 and older. The goal is to see if it reduces pain and headache days, and to find out which patients respond best. Researchers will also look at frailty and nutrition as possible predictors. The study plans to enroll 100 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pulsed radiofrequency (PRF) applied to the greater occipital nerve

What this could lead to

If successful, this could offer a safe, non-drug option to ease chronic migraine in older adults and help doctors predict who will benefit most.

What could go wrong

This is a small, early-stage study with no control group, so results may not be conclusive. The procedure may not work for everyone, and benefits could be temporary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••