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New drug combo aims to improve lymphoma treatment

NCT ID NCT06425302

Ongoing Disease control Sponsor: Celgene Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a new combination of drugs, golcadomide and rituximab, in 90 people with newly diagnosed advanced follicular lymphoma. The goal is to see if this combination can improve complete remission rates compared to standard treatments. The study is active but no longer recruiting participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
golcadomide (a drug) combined with rituximab (a drug)
What this could lead to
If successful, this combination could offer a new first-line treatment option for advanced follicular lymphoma, potentially improving remission rates.
What could go wrong
This is a phase 2 trial with only 90 participants, so results are preliminary. The combination may not prove more effective than standard treatments, and side effects are still being evaluated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

follicular lymphoma lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYMPHOMA, FOLLICULAR

Contacts and locations

Locations

  • Local Institution - 0005

    Jacksonville, Florida, 32224, United States

  • Local Institution - 0019

    Westwood, Kansas, 66205, United States

  • Local Institution - 0022

    Washington D.C., District of Columbia, 20007, United States

  • Local Institution - 0026

    Tampa, Florida, 33606, United States

  • Local Institution - 0031

    Rochester, Minnesota, 55905, United States

  • Local Institution - 0035

    San Francisco, California, 94143, United States

  • Local Institution - 0046

    Liverpool, New South Wales, 2170, Australia

  • Local Institution - 0049

    Santiago, Santiago Metropolitan, 7500921, Chile

  • Local Institution - 0050

    Santiago, Santiago Metropolitan, 7580206, Chile

  • Local Institution - 0052

    Salt Lake City, Utah, 84106, United States

  • Local Institution - 0055

    Anchorage, Alaska, 99508, United States

  • Local Institution - 0056

    São Paulo, 05652-900, Brazil

  • Local Institution - 0058

    São Paulo, 04543-000, Brazil

  • Local Institution - 0060

    Rio de Janeiro, 22250-905, Brazil

  • Local Institution - 0061

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

  • Local Institution - 0064

    Toronto, Ontario, M5G 2M9, Canada

  • Local Institution - 0070

    South Brisbane, Queensland, 4101, Australia

  • Local Institution - 0075

    Naples, 80131, Italy

  • Local Institution - 0076

    Bologna, 40138, Italy

  • Local Institution - 0085

    Seoul, Seoul-teukbyeolsi [Seoul], 03080, South Korea

  • Local Institution - 0086

    Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea

  • Local Institution - 0092

    Kaohsiung City, 83301, Taiwan

  • Local Institution - 0094

    Kaohsiung City, 807, Taiwan

  • Local Institution - 0100

    Busan, Pusan-Kwangyǒkshi, 49241, South Korea

  • Local Institution - 0101

    Saint-Cloud, Hauts-de-Seine, 92210, France

  • Local Institution - 0103

    Lille, Nord, 59000, France

  • Local Institution - 0105

    Nottingham, NG5 1PB, United Kingdom

  • Local Institution - 0111

    Henderson, Nevada, 89074, United States

  • Local Institution - 0112

    Canterbury, Kent, CT1 3NG, United Kingdom

  • Local Institution - 0115

    Edinburgh, Midlothian, EH4 2XU, United Kingdom

  • Local Institution - 0118

    Paris, 75010, France

  • Local Institution - 0121

    Poitiers, Vienne, 86021, France

  • Local Institution - 0123

    Taipei, 10002, Taiwan

  • Local Institution - 0152

    Birmingham, Alabama, 35294-3300, United States

  • Local Institution - 0175

    Southampton, Hampshire, SO16 0YD, United Kingdom

  • Local Institution - 0179

    Rozzano, Milano, 20089, Italy

  • Local Institution - 0180

    Phoenix, Arizona, 85054, United States

  • Local Institution - 0181

    Traralgon, Victoria, 3844, Australia

  • Local Institution - 0183

    Hackensack, New Jersey, 07601, United States

  • Local Institution - 0185

    Warsaw, Masovian Voivodeship, 01-748, Poland

  • Local Institution - 0186

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-168, Poland

  • Local Institution - 0187

    Skórzewo, Greater Poland Voivodeship, 60-185, Poland

  • Local Institution - 0188

    Chemnitz, Saxony, 09116, Germany

  • Local Institution - 0189

    Dresden, 01307, Germany

  • Local Institution - 0190

    Tucson, Arizona, 85711, United States

  • Local Institution - 0191

    Madrid, 28040, Spain

  • Local Institution - 0192

    Valencia, Valenciana, Comunitat, 46017, Spain

  • Local Institution - 0196

    Palma, Balears [Baleares], 07120, Spain

  • Local Institution - 0197

    Regensburg, Bavaria, 93049, Germany

  • Local Institution - 0198

    Rome, Lazio, 00133, Italy

  • Local Institution - 0201

    Norfolk, Virginia, 23502, United States

  • Local Institution - 0202

    Seattle, Washington, 98109, United States

  • Local Institution - 0205

    Chicoutimi, Quebec, G7H 5H6, Canada

  • Local Institution - 0208

    West Palm Beach, Florida, 33401, United States

  • Local Institution - 0209

    Fort Myers, Florida, 33901, United States

  • Local Institution - 0210

    St. Petersburg, Florida, 33705, United States

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