New 'Four-in-One' antibody takes on Hard-to-Treat lymphoma

NCT ID NCT05623982

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called GNC-038, a tetra-specific antibody designed to target cancer cells in people with Non-Hodgkin's lymphoma that has come back or not responded to treatment. About 40 adults will receive the drug by IV to see if it is safe and can shrink tumors. The goal is to find the best dose and check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GNC-038 (a tetra-specific antibody given by IV infusion)

What this could lead to

If successful, this could point toward a new treatment option for people with Non-Hodgkin's lymphoma that has not responded to other therapies.

What could go wrong

This is an early-phase trial with only 40 participants, so results may not apply broadly. The drug may cause side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Harbin First Hospital

    RECRUITING

    Haerbin, Heilongjing, China

    Contact

  • Qingdao Central Hospital

    RECRUITING

    Qingdao, Shandong, China

    Contact