First human trial of 'Tianasen' offers hope for kids with devastating genetic disorder

NCT ID NCT07363603

Summary

This study is testing a new drug called Tianasen (ASO-GNAO1) for children with a severe genetic brain disorder caused by a specific GNAO1 gene mutation. The drug is designed to target and reduce the harmful protein produced by the faulty gene, with the goal of slowing or stopping the progression of seizures and movement problems. Five children, aged 1 to 14, will receive the drug via spinal injections over a year while doctors closely monitor their symptoms and safety.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.