Brain's Waste-Cleaning system may hold key to early MS detection

NCT ID NCT06274671

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 25 times

Summary

This study looks at whether the brain's natural waste-cleaning system, called the glymphatic system, works differently in people with Clinically Isolated Syndrome (CIS), which can be an early sign of multiple sclerosis (MS). Researchers will use special MRI scans to compare 30 adults with CIS to healthy volunteers. The goal is to find out if these changes can help detect MS earlier and understand how the disease progresses.

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Contacts and locations

Locations

  • Royal Devon University Healthcare NHS Foundation Trust

    Exeter, United Kingdom

  • University of Exeter

    Exeter, United Kingdom

Conditions

Explore the condition pages connected to this study.