Hidden fat lumps may sabotage insulin: new study investigates

NCT ID NCT02748434

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether small, hard-to-see fat lumps under the skin (called subclinical lipohypertrophy) change how insulin is absorbed in people with diabetes. Researchers planned to enroll 20 adults with type 1 or type 2 diabetes who use insulin and had these hidden lumps. They measured blood sugar levels using continuous glucose monitors to see if injecting insulin into these areas affects glucose control. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus lipodystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gerontology Research Lab

    Vancouver, British Columbia, V5Z 1M9, Canada

  • Vancouver General Hospital Diabetes Centre

    Vancouver, British Columbia, V5Z 1M9, Canada