Could a popular Weight-Loss drug help obese women beat uterine precancer without surgery?

NCT ID NCT07107334

First seen Jan 04, 2026 · Last updated May 05, 2026 · Updated 20 times

Summary

This pilot study tests whether adding a GLP-1RA weight-loss drug (like semaglutide) to a hormonal IUD can reverse precancerous changes in the uterus lining of obese women. About 20 women who are not good candidates for hysterectomy or wish to preserve fertility will be followed for up to 12 months. The goal is to see if the combination can clear the precancer, potentially avoiding major surgery or enabling pregnancy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32608, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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