500 transgender adults to be tracked for 5 years in landmark study on Gender-Affirming care outcomes

NCT ID NCT07480590

Recruiting now Knowledge-focused Sponsor: Region Skane Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

The GLOW study is following 500 adults seeking gender-affirming care at a specialized clinic in Sweden. Researchers will track changes in mental health, quality of life, work capacity, and healthcare use over five years. The goal is to understand what factors lead to better outcomes and to reduce stigma around gender dysphoria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could clarify which types of gender-affirming care improve quality of life and mental health, helping to guide future treatment decisions.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may take years and might not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Gender Dysphoria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GENDER DYSPHORIA, ADULT

Contacts and locations

Locations

The Gender Dysphoria Clinic at Skåne University Hospital, Malmö, Sweden
RECRUITING

Malmö, Malmö, Sweden

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