New hope for aggressive lymphoma with gene mutation?

NCT ID NCT07240194

First seen Nov 20, 2025 · Last updated Jun 15, 2026 · Updated 24 times

Summary

This study tests a combination of three drugs (glofitamab, a PD-1 inhibitor, and lenalidomide) in 24 people with a specific, hard-to-treat type of large B-cell lymphoma that has come back or not responded to treatment. The goal is to see if this combination can shrink or eliminate the cancer. Participants must have a TP53 gene change, which often makes the cancer harder to treat.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital with Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.