New combo therapy targets Hard-to-Treat lymphoma
NCT ID NCT06054776
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a combination of three drugs—acalabrutinib, obinutuzumab, and glofitamab—can safely treat mantle cell lymphoma that has come back or not responded to prior therapy. The drugs work by blocking cancer growth signals and helping the immune system attack cancer cells. About 40 adults with this type of lymphoma will participate. The main goals are to check side effects and see how many patients achieve a complete response (no cancer detected).
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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