New eye drop takes on pesky eyelash mites

NCT ID NCT07400965

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental eye drop called GLK-321 in 250 adults with Demodex blepharitis, a condition where tiny mites cause debris at the base of eyelashes. Participants will receive either a low, mid, or high dose of the drug, or a placebo, for 6 weeks. The main goal is to see if the drug safely clears the eyelash debris.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
GLK-321 eye drops
What this could lead to
If it works, this could lead to a new prescription eye drop that clears the eyelash debris caused by Demodex mites.
What could go wrong
This is an early Phase 2 trial with only 250 people, so results may not hold up in larger studies. The drug may cause eye irritation or not work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Glaukos Clinical Study Site

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact Email: •••••@•••••

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