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Brain cancer breakthrough? major trial tests Triple-Threat treatment

NCT ID NCT06556563

Recruiting now Disease control Sponsor: NovoCure GmbH Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing whether adding the immunotherapy drug pembrolizumab to the standard treatment of Optune (a wearable device that uses electric fields) and chemotherapy helps people with newly diagnosed glioblastoma live longer. The study will involve 741 adults who have recently finished initial radiation and chemo. Participants will be randomly assigned to receive either the real immunotherapy drug or a placebo, in addition to the standard Optune and chemo treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital (Cambridge University Hospitals NHS Foundation Trust)

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Hospitalier Universitaire Vaudois (CHUV)

    RECRUITING

    Lausanne, 1005, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire de Lyon

    RECRUITING

    Bron, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centrum Onkologii

    RECRUITING

    Bydgoszcz, 85-796, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chaim Sheba Medical Center

    RECRUITING

    Ramat Gan, 5265601, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Charité Campus Virchow-Klinikum

    RECRUITING

    Berlin, 10117, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Groupe Hospitalier Pitie - Salpetriere

    RECRUITING

    Paris, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hoag Memorial Hospital Presbyterian

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hokkaido University Hospital

    RECRUITING

    Hokkaido, 060-8648, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital Saint-Louis

    RECRUITING

    Paris, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hopital de la Timone

    RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitari i Politécnic La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Clínico San Carlos

    ENROLLING_BY_INVITATION

    Madrid, Madrid, 28040, Spain

  • Hospital Universitario La Paz

    RECRUITING

    Madrid, 28046, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, 28034, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Reina Sofia

    RECRUITING

    Córdoba, 14004, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Virgen de las Nieves

    RECRUITING

    Granada, 18014, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Virgen del Rocio

    RECRUITING

    Seville, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Huntsman Cancer Institute, University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IRCCS Istituto Clinico Humanitas

    RECRUITING

    Rozzano, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inova Schar Cancer Institute

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Català d'Oncologia de L'Hospitalet (ICO L'Hospitalet)

    RECRUITING

    Barcelona, 08908, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Claudius Regaud

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • John Theurer Cancer Center/ Hackensack Meridian Health

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kanazawa University Hospital

    RECRUITING

    Ishikawa, 920-8641, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kumamoto University Hospital

    RECRUITING

    Kumamoto, 860-8556, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kyorin University Hospital

    RECRUITING

    Mitaka, 181-8611, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kyoto University Hospital

    RECRUITING

    Kyoto, 606-8507, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kyushu University Hospital

    RECRUITING

    Fukuoka, 812-8582, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Masonic Cancer Center, University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic - Florida

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic - Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Hospital

    RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Miami Cancer Institute

    RECRUITING

    Miami, Florida, 33176, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Montefiore Medical Center- Montefiore Medical Park

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nagoya University Hospital

    RECRUITING

    Nagoya, 466-8560, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Narodowy Instytut Onkologii

    RECRUITING

    Gliwice, 44-102, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Center Hospital

    RECRUITING

    Tokyo, 104-0045, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nemocnice Na Homolce

    RECRUITING

    Prague, 150 30, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwell Health

    RECRUITING

    Lake Success, New York, 11042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northwestern Memorial Hospital

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Bellaria

    RECRUITING

    Bologna, 40139, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale del Mare

    RECRUITING

    Naples, 80147, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queen Elizabeth

    RECRUITING

    Birmingham, B15 2TH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rabin Medical Center- Beilinson Hospital

    RECRUITING

    Petah Tikva, 4941492, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rambam Medical Center

    RECRUITING

    Haifa, 3109601, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Royal Marsden

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Saitama Medical University International Medical Center

    RECRUITING

    Saitama, 350-1298, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Southampton General Hospital

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Cancer Institute

    RECRUITING

    Palo Alto, California, 94305, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Swedish Medical Center

    RECRUITING

    Seattle, Washington, 98122, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tel-Aviv Sourasky Medical Center

    RECRUITING

    Tel Aviv, 64239, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Christie Hospital

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The University of Texas

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Thomas Jefferson University, Sidney Kimmel Comprehensive Cancer Center, Clinical Trials Organization

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tohoku University Hospital

    RECRUITING

    Sendai, 980-8574, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • U.O.C. Immunoterapia Oncologica A.O.U. Senese, Policlinico Santa Maria alle Scotte

    RECRUITING

    Siena, 53100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UF Health Neuromedicine

    RECRUITING

    Gainesville, Florida, 32608, United States

    Contact Email: •••••@•••••

  • UOC Oncologia Medica 1 Istituto Oncologico Veneto IOV-IRCCS

    RECRUITING

    Padua, 35128, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Basel Medical Oncology

    RECRUITING

    Basel, 4031, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Frankfurt

    RECRUITING

    Frankfurt, 60528, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Zurich

    RECRUITING

    Zurich, 8091, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Kentucky Medical Center

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Southern California

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas, MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsklinikum Essen

    RECRUITING

    Essen, 45147, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, CF14 2TL, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Weston Park Hospital

    RECRUITING

    Sheffield, S10 2SJ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

GLIOBLASTOMA