New drug shows promise in slowing lung scarring

NCT ID NCT03865927

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called GKT137831 in 58 people with idiopathic pulmonary fibrosis (IPF), a disease that causes progressive lung scarring. The drug aims to reduce lung damage caused by harmful molecules called reactive oxygen species. Researchers measured changes in blood markers of oxidative stress and collagen breakdown to see if the drug could slow disease progression.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Temple University Medical Center

    Philadelphia, Pennsylvania, 19140, United States

  • Tulane University Medical Center

    New Orleans, Louisiana, 70112, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Michigan Medical Center

    Ann Arbor, Michigan, 48109, United States

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