Gut hormone may control Post-Meal blood pressure drops

NCT ID NCT06934473

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how a natural gut hormone called GIP affects blood pressure after a meal. Sixteen healthy adults will receive either a GIP-blocking drug, a GIP-activating drug, or a placebo during a tilt-table test. The goal is to see if blocking or boosting GIP changes how blood pressure responds after eating.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GIP(3-30)NH2 (a blocker of the GIP hormone receptor) and GIP(1-42) (an activator of the GIP hormone receptor)

What this could lead to

If successful, this could clarify how the gut hormone GIP influences blood pressure after meals, potentially pointing toward new ways to manage dizziness or fainting.

What could go wrong

This is a very small, early-stage study in healthy volunteers, not patients. It is designed to understand basic biology, not to test a treatment. Results may not apply to people with blood pressure problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Clinical Metabolic Research

    NOT_YET_RECRUITING

    Copenhagen, Hellerup, 2900, Denmark

  • Center for Clinical Metabolic Research

    RECRUITING

    Copenhagen, Hellerup, 2900, Denmark

    Contact

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