Gut hormone may control Post-Meal blood pressure drops
NCT ID NCT06934473
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how a natural gut hormone called GIP affects blood pressure after a meal. Sixteen healthy adults will receive either a GIP-blocking drug, a GIP-activating drug, or a placebo during a tilt-table test. The goal is to see if blocking or boosting GIP changes how blood pressure responds after eating.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- GIP(3-30)NH2 (a blocker of the GIP hormone receptor) and GIP(1-42) (an activator of the GIP hormone receptor)
- What this could lead to
- If successful, this could clarify how the gut hormone GIP influences blood pressure after meals, potentially pointing toward new ways to manage dizziness or fainting.
- What could go wrong
- This is a very small, early-stage study in healthy volunteers, not patients. It is designed to understand basic biology, not to test a treatment. Results may not apply to people with blood pressure problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Center for Clinical Metabolic Research
NOT_YET_RECRUITINGCopenhagen, Hellerup, 2900, Denmark
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Center for Clinical Metabolic Research
RECRUITINGCopenhagen, Hellerup, 2900, Denmark