New balloon treatment shows promise for long heart blockages

NCT ID NCT05471245

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a special balloon coated with sirolimus, a drug that helps prevent arteries from narrowing again after angioplasty. It included 110 adults with stable or unstable coronary artery disease who had long blockages (at least 25 mm) in their heart arteries. The main goals were to measure how well the artery stayed open after 9 months and to track any serious heart problems like heart attacks or the need for another procedure.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary restenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AULSS 2 Marca Trevigiana Ospedale di Conegliano

    Conegliano, Italy/TV, 31015, Italy

  • Centro Cardiologico Monzino

    Milan, Italy/MI, 20138, Italy

  • IRCCS Ospedale Galeazzi Sant'Ambrogio

    Milan, Italy/MI, 20157, Italy

  • IRCCS Ospedale San Raffaele

    Milan, Italy/MI, 20132, Italy

  • Istituto Clinico Humanitas

    Rozzano, Italy/MI, 20089, Italy

  • Policlinico Tor Vergata

    Rome, Italy/RM, 00133, Italy

  • Policlinico Universitario Campus Bio-Medico

    Roma, Italy/RM, 00128, Italy