New hope for advanced breast cancer: personalized drug combo trial launches

NCT ID NCT05933395

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 32 times

Summary

This study tests whether certain drug combinations can help people with advanced ER+/HER2- breast cancer whose disease has stopped responding to standard CDK4/6 inhibitor pills. About 135 postmenopausal women will receive one of several treatment arms based on their tumor's genetic profile. The goal is to see if these combinations can shrink tumors or keep them stable for at least 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dartmouth Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 03756, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.