Genetic score may guide breast cancer prevention decisions
NCT ID NCT04474834
First seen Mar 07, 2026 · Last updated May 13, 2026 · Updated 12 times
Summary
This study looks at whether adding a polygenic risk score (a measure of many small genetic factors) to standard risk tools helps women ages 35-75 at high risk for breast cancer decide on prevention steps, such as taking medication, having risk-reducing surgery, or getting extra imaging. About 737 participants will report their intentions and follow-up for 10 years. The goal is to improve personalized prevention and reduce breast cancer cases.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Mayo Clinic
Scottsdale, Arizona, 85259, United States
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Mayo Clinic
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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Northwestern University
Evanston, Illinois, 60208, United States
Conditions
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