Hidden genetic risks found in normal fetuses?
NCT ID NCT06211348
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether adding genomic sequencing to standard prenatal tests can find hidden genetic risks in fetuses that appear normal on ultrasound. Researchers will enroll 1,000 pregnant people who are already having amniocentesis or CVS for routine reasons. The goal is to see how often extra genetic findings turn up in these healthy-looking pregnancies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Genomic sequencing
- What this could lead to
- If successful, this could show that genomic sequencing provides useful genetic information beyond standard tests for pregnancies with normal-looking fetuses.
- What could go wrong
- This is an early observational study, not a treatment trial. It may find variants of uncertain significance, causing anxiety without clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States