New implant zaps nerve to treat sleep apnea without CPAP
NCT ID NCT05592002
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a device called the Genio® System, which is implanted under the chin and stimulates a nerve to keep the airway open during sleep. It is for people with obstructive sleep apnea who have not been helped by CPAP machines and have a specific type of airway collapse. The study will track 124 participants for 12 months to see if the device reduces breathing pauses and improves oxygen levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Genio® dual-sided hypoglossal nerve stimulation system (implantable device)
What this could lead to
If it works, this could offer a new treatment option for people with obstructive sleep apnea who cannot use a CPAP machine, especially those with a specific type of airway collapse.
What could go wrong
This is an early-stage study with no control group, so results may not prove the device works better than no treatment or other options. The device requires surgery, and long-term safety and effectiveness are still unknown.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Bogan Sleep Consultants, LLC
Columbia, South Carolina, 29201, United States
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Center for ENT and Allergy, PC Ascension Medical Group
Carmel, Indiana, 46032, United States
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Colorado ENT & Allergy
Colorado Springs, Colorado, 80923, United States
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ENT and Allergy Associates of Florida, LLC
Boca Raton, Florida, 33487, United States
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Eastern Virginia Medical School
Norfolk, Virginia, 23507, United States
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Hospital of the University Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Massachusetts Eye & Ear
Boston, Massachusetts, 02114, United States
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PharmaDev Clinical Research Institute,
Miami, Florida, 33176, United States
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Thomas Jefferson University Department of Otolaryngology
Philadelphia, Pennsylvania, 19107, United States
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University of Iowa Institute for Clinical & Translational Science
Iowa City, Iowa, 52242, United States
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University of Kansas
Kansas City, Kansas, 66160, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Rochester
Rochester, New York, 14627, United States
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University of South Florida
Tampa, Florida, 33620, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States