Study explores how genetic risk info shapes BRCA Carriers' health choices

NCT ID NCT03396341

Recruiting now Knowledge-focused Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how women with BRCA1 or BRCA2 gene mutations respond to learning about additional genetic risk factors. Researchers will follow about 800 women who have not had breast cancer, asking them to complete questionnaires and provide saliva or cheek swab samples. The goal is to see how this extra genetic information affects their decisions about preventive surgeries or cancer screening.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand how genetic risk information influences women's choices about breast cancer prevention, potentially improving counseling and decision-making support.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly improve health outcomes. Results may not apply to non-English speakers or women under 25.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRCA1/2 GENETIC TESTING

Contacts and locations

Locations

Abramson Cancer Center at University of Pennsylvania Medical Center (Data Collection Only)
RECRUITING

Philadelphia, Pennsylvania, 19104-4283, United States
Dana Farber Cancer Institute (Data Collection Only)
RECRUITING

Boston, Massachusetts, 02115, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Commack
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Nassau
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester
RECRUITING

Harrison, New York, 10604, United States
Memorial Sloan-Kettering at Basking Ridge
RECRUITING

Basking Ridge, New Jersey, 07920, United States

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