Family DNA hunt aims to uncover myeloma risk genes
NCT ID NCT02853214
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study collected blood samples from nearly 1,900 people in families where at least two members have a type of dysglobulinemia, including multiple myeloma, MGUS, or Waldenström's disease. Researchers will analyze the DNA to look for genetic variations that might increase the risk of developing these conditions. The goal is to better understand what causes these diseases, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify genetic risk factors for multiple myeloma and related conditions, potentially guiding future screening or prevention strategies.
- What could go wrong
- This is an observational genetic study, not a treatment trial. It may not find clear risk genes, and any findings would need years of further research before they could help patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CH William Morey, Service d'Hémato-Oncologie
Chalon-sur-Saône, 71321, France
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CH d'Avignon
Avignon, 84902, France
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CH de Blois Service d'Hématologie
Blois, France
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CH de Rodez
Rodez, 12027, France
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CHR-Metz-Thionville, Hôpital de Mercy, Service d'Hématologie
Metz, 57085, France
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CHU Albert Michallon
Grenoble, 38043, France
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CHU Amiens Picardie
Amiens, 80054, France
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CHU Carémeau
Nîmes, 30029, France
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CHU Groupe Hospitalier Sud Hématologie Clinique
Amiens, France
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CHU Morvan
Brest, France
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CHU d'ABBEVILLE
Abbeville, 80100, France
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CHU d'Annecy
Metz-Tessy, 74374, France
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CHU de Besançon
Besançon, 25030, France
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CHU de Chartres
Chartres, 28018, France
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CHU de Nancy, Hôpital de Brabois
Vandœuvre-lès-Nancy, France
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CHU de Poitiers
Poitiers, 86021, France
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CHU de Rennes Hôpital Sud
Rennes, France
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CHU-HÔTEL -Dieu de Nantes
Nantes, 44093, France
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Centre Hospitalier de Dunkerque
Dunkirk, 59 385, France
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Centre Hospitalier de Valence
Valence, 26953, France
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Centre Jean Bernard Clinique Victor Hugo
Le Mans, 72000, France
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Département d'Hématologie à l'Institut de Cancérologie de la Loire
Saint-Priest-en-Jarez, 42270, France
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Département d'Oncogénitique - Centre Jean Perrin
Clermont-Ferrand, 63011, France
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Département d'Oncogénétique, Centre Paoli Calmettes
Marseille, France
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GHM, Institut Daniel Hollard
Grenoble, 38000, France
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Hospices Civils de Lyon
Pierre-Bénite, 69495, France
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Hématolgie- Hôpital privé Cesson-Sévigné
Cesson-Sévigné, 35510, France
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Hôpital Avicenne Service d'Hématologie
Bobigny, France
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Hôpital Privé de Villeneuve d'Ascq
Villeneuve-d'Ascq, 59650, France
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Hôpital Purpan Service d'Hématologie
Toulouse, 31059, France
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Hôpital Robert Debré Service du Professeur A. DELMER Hématologie Clinique
Reims, France
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Hôpital Saint-Eloi, Département d'Hématologie clinique
Montpellier, 34295, France
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Hôpital St Antoine Service des maladies du Sang
Paris, France
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Hôpital Sud Francilien
Corbeil-Essonnes, 91100, France
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Hôpital de Saint- Germain en Laye
Saint-Germain-en-Laye, 78100, France
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Hôpital de l'Archet 1
Nice, 06202, France
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Institut Curie
Paris, 75248, France
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Jean Paul FermandService Immuno-Hématologie Hôpital Saint Louis
Paris, France
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Service d'Hématologie Clinique, CHU de Dijon
Dijon, 21000, France
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Service d'Hématologie clinique et Thérapie Cellulaire, CHU de BORDEAUX
Bordeaux, France
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Service d'Hématologie, CHU de Versailles
Le Chesnay, 78150, France
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Service d'Onco-hématologie, Hôpital Saint-Vincent GH-ICL
Lille, 59000, France
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Service d'Oncologie Médical, Centre Azuréen de Canrérologie-1
Mougins, 06250, France
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Service d'Oncologie-Radiothérapie - CHU Pointe-à-Pitre/Abymes Guadeloupe
Pointe à Pitre, Guadeloupe, 97159, France
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Service d'hématologie Clinique
Caen, 14000, France
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Service de Médecine Interne-Hématologie, CHU de Fort de France Fort de France
Fort-de-France, Martinique, 97200, France
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Service des Maladies du Sang CHU Lille
Lille, France