One-Time infusion aims to fix faulty immune cells

NCT ID NCT06876363

Summary

This early-stage study is testing a new one-time gene therapy called EN-374 for people with X-linked chronic granulomatous disease (X-CGD), a rare disorder where the immune system can't fight off serious infections. The main goals are to see if the treatment is safe and if it can help the body produce properly working infection-fighting cells. The study will first enroll adults, then later include children as young as 3 months old.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Columbia University Irving Medical Center, Morgan Stanley Children's Hospital

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Duke University

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins All Children's Hospital

    RECRUITING

    St. Petersburg, Florida, 33701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55454, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Utah, Primary Children's Hospital

    RECRUITING

    Salt Lake City, Utah, 84113, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.