One-Shot gene therapy tested for rare copper disease

NCT ID NCT04537377

Summary

This is an early-stage study testing a single dose of an experimental gene therapy called VTX-801 in adults with Wilson's Disease. The main goal is to check if the treatment is safe and to see how it affects the body's copper levels over five years. Researchers will give the therapy by IV and then carefully monitor participants, including trying to reduce their standard medications.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, 8200, Denmark

  • Advent Health

    Orlando, Florida, 32803, United States

  • Royal Surrey County Hospital

    Guildford, Surrey, GU2 7XX, United Kingdom

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

  • University Hospital Essen

    Essen, 45147, Germany

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75235, United States

  • Universitätsklinikum Tübingen (UKT)

    Tübingen, 72076, Germany

  • Wake Forest School of Medicine

    Winston-Salem, North Carolina, 27157, United States

  • Yale University School of Medecine

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.