One-Time gene shot aims to free patients from monthly eye injections

NCT ID NCT07007065

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a single gene therapy injection can reduce the need for frequent eye injections in people with wet age-related macular degeneration (AMD), a leading cause of vision loss. About 561 participants aged 50+ who have been receiving regular eye injections will be randomly assigned to receive either the experimental gene therapy or continue with standard injections. The main goal is to see if the one-time treatment can safely preserve vision while significantly cutting down the number of injections needed over five years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advanced Research, LLC /ID# 276526
RECRUITING

Deerfield Beach, Florida, 33064-1346, United States
Advanced Vision Surgery Center /ID# 264208
RECRUITING

Longmont, Colorado, 80503, United States
American Vision Partners /ID# 264615
RECRUITING

Sun City, Arizona, 85351, United States
Associated Retinal Consultants /ID# 263289
RECRUITING

Royal Oak, Michigan, 48073, United States
Austin Clinical Research, LLC /ID# 263229
RECRUITING

Austin, Texas, 78750-2298, United States
Austin Retina Associates - Austin /ID# 266770
RECRUITING

Austin, Texas, 78705, United States
Azienda Ospedaliero Universitaria Careggi /ID# 265739
RECRUITING

Florence, Firenze, 50134, Italy
Azienda Ospedaliero Universitaria delle Marche /ID# 265305
RECRUITING

Ancona, 60020, Italy
Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale S.Anna /ID# 276017
RECRUITING

Cona, Ferrara, 44124, Italy
Bristol Eye Hospital /ID# 266155
RECRUITING

Bristol, BS1 2LX, United Kingdom
Budapest Retina Associates /ID# 265208
RECRUITING

Budapest, 1133, Hungary
CHU Bordeaux - Hopital Pellegrin /ID# 265123
RECRUITING

Bordeaux, Nouvelle-Aquitaine, 33076, France
Centre Hospitalier Intercommunal de Creteil /ID# 265080
RECRUITING

Créteil, Val-de-Marne, 94010, France
Centre Hospitalier National d'Ophtalmologie Quinze-Vingts /ID# 265125
RECRUITING

Paris, Île-de-France Region, 75571, France
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu /ID# 265077
RECRUITING

Nantes, Pays de la Loire Region, 44000, France
Centre d'Oftalmologia Barraquer /ID# 266631
RECRUITING

Barcelona, 08021, Spain
Charleston Neuroscience Institute /ID# 264037
RECRUITING

Bluffton, South Carolina, 29910, United States
Charleston Neuroscience Institute /ID# 276425
RECRUITING

Charleston, South Carolina, 29414, United States
Colorado Retina Associates /ID# 263247
RECRUITING

Lakewood, Colorado, 80228, United States
Debreceni Egyetem-Klinikai Kozpont /ID# 265453
RECRUITING

Debrecen, Hajdú-Bihar, 4032, Hungary
Edith Wolfson Medical Center /ID# 266304
RECRUITING

Holon, Central District, 5822012, Israel
Emanuelli Research & Development Center /ID# 264350
RECRUITING

Arecibo, 00612, Puerto Rico
Erie Retina Research /ID# 263287
RECRUITING

Erie, Pennsylvania, 16507, United States
Florida Retina Institute - Lake Mary /ID# 263288
RECRUITING

Lake Mary, Florida, 32746, United States
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 276032
RECRUITING

Rome, Roma, 00168, Italy
Ganglion Orvosi Kozpont /ID# 265210
RECRUITING

Pécs, Baranya, 7621, Hungary
Gloucestershire Royal Hospital /ID# 276072
RECRUITING

Gloucester, Gloucestershire, GL1 3NN, United Kingdom
Hadassah Medical Center-Hebrew University /ID# 264300
RECRUITING

Jerusalem, 91120, Israel
Hopital Edouard Herriot /ID# 265072
RECRUITING

Lyon, Auvergne-Rhône-Alpes, 69003, France
Hospital Arruzafa /ID# 280175
RECRUITING

Córdoba, Cordoba, 14012, Spain
Hospital Clinico Universitario Lozano Blesa /ID# 263158
RECRUITING

Zaragoza, 50009, Spain
Hospital Universitari Vall d'Hebron /ID# 263301
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre /ID# 263544
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Puerta de Hierro - Majadahonda /ID# 263179
RECRUITING

Majadahonda, Madrid, 28222, Spain
Hôpital Fondation Adolphe de Rothschild /ID# 265081
RECRUITING

Paris, 75019, France
Institut Clínic d'Oftalmologia (ICOF). Hospital Clínic d'Oftalmologia. /ID# 263152
RECRUITING

Barcelona, 08028, Spain
Kaplan Medical Center /ID# 264399
RECRUITING

Rehovot, Central District, 7660101, Israel
Kepler Universitaetsklinikum GmbH /ID# 264493
RECRUITING

Linz, Upper Austria, 4020, Austria
Klinikum Ludwigshafen /ID# 275448
RECRUITING

Ludwigshafen am Rhein, Rhineland-Palatinate, 67063, Germany
LMU Klinikum - Campus Innenstadt /ID# 264285
RECRUITING

Munich, Bavaria, 80336, Germany
Liverpool University Hospitals NHS Foundation Trust /ID# 265854
RECRUITING

Liverpool, Merseyside, L9 7AL, United Kingdom
Mayo Clinic - Minnesota /ID# 263977
RECRUITING

Rochester, Minnesota, 55905, United States
Medical Center -Vereya /ID# 275728
RECRUITING

Stara Zagora, 6000, Bulgaria
Medizinische Hochschule Hannover /ID# 264281
RECRUITING

Hanover, Lower Saxony, 30625, Germany
Medizinische Universitaet Graz /ID# 264511
RECRUITING

Graz, Styria, 8010, Austria
Medizinische Universitaet Innsbruck /ID# 264502
RECRUITING

Innsbruck, Tyrol, 6020, Austria
Midwest Eye Institute North Indianapolis /ID# 264031
RECRUITING

Carmel, Indiana, 46290, United States
Midwest Retina /ID# 263231
RECRUITING

Dublin, Ohio, 43016, United States
Moorfields Eye Hospital /ID# 267227
RECRUITING

London, Greater London, EC1V 2PD, United Kingdom
OCIPSMAED St. Luka /ID# 275727
RECRUITING

Plovdiv, 4002, Bulgaria
Orange County Retina Medical Group /ID# 266612
RECRUITING

Santa Ana, California, 92705, United States
Rabin Medical Center /ID# 266449
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Retina Associates of Southern California /ID# 263056
RECRUITING

Huntington Beach, California, 92647, United States
Retina Centre of Ottawa /ID# 263803
RECRUITING

Ottawa, Ontario, K2B 7E9, Canada
Retina Consultants of America /ID# 264038
RECRUITING

Mt. Pleasant, South Carolina, 29464, United States
Retina Consultants of Minnesota (RCM) - Edina Retina Clinic /ID# 279427
RECRUITING

Edina, Minnesota, 55435, United States
Retina Consultants of South Carolina - Ladson /ID# 277596
RECRUITING

Ladson, South Carolina, 29456, United States
Retina Consultants of Southern Colorado /ID# 263284
RECRUITING

Colorado Springs, Colorado, 80909, United States
Retina Consultants of Texas - Westover /ID# 264209
RECRUITING

San Antonio, Texas, 78251, United States
Retina Institute - St. Louis /ID# 263985
RECRUITING

St Louis, Missouri, 63128, United States
Retina Specialist /ID# 264633
RECRUITING

Towson, Maryland, 21204, United States
Retina Vitreous Consultants LLP business DBA as Retina Group of Florida /ID# 264631
RECRUITING

Fort Myers, Florida, 33917, United States
Retinal Consultants - Sacramento - Greenback Lane /ID# 263983
RECRUITING

Sacramento, California, 95841, United States
Retinal Diagnostic Center /ID# 263054
RECRUITING

Campbell, California, 95008, United States
Rocky Mountain Retina Consultants /ID# 263266
RECRUITING

Murray, Utah, 84107, United States
Southeast Retina Center /ID# 263264
RECRUITING

Augusta, Georgia, 30909, United States
Specialized Eye Hospital for Active Treatment - Burgas OOD /ID# 275729
RECRUITING

Burgas, 8005, Bulgaria
Specialized Hospital for Active Treatment of Eye Diseases Zora /ID# 275730
RECRUITING

Sofia, 1784, Bulgaria
Specijalna bolnica Svjetlost /ID# 276051
RECRUITING

Zagreb, City of Zagreb, 10000, Croatia
Springfield Clinic Main Campus /ID# 265202
RECRUITING

Springfield, Illinois, 62703-2403, United States
Star Retina /ID# 266386
RECRUITING

Burleson, Texas, 76028, United States
Sunderland Royal Hospital /ID# 266664
RECRUITING

Sunderland, SR4 7TN, United Kingdom
The Retina Care Center /ID# 263263
RECRUITING

Baltimore, Maryland, 21209, United States
The Retina Clinic London /ID# 266156
RECRUITING

London, Greater London, W1G 7LB, United Kingdom
The Retina Partners /ID# 263265
RECRUITING

Encino, California, 91436, United States
UZ Gent /ID# 261300
RECRUITING

Ghent, Oost-Vlaanderen, 9000, Belgium
Unidade Local de Saude de Coimbra, EPE /ID# 264657
RECRUITING

Coimbra, 3000-075, Portugal
Unidade Local de Saude de Sao Jose, EPE /ID# 264655
RECRUITING

Lisbon, 1150-199, Portugal
Universitaetsklinikum Bonn /ID# 264279
RECRUITING

Bonn, North Rhine-Westphalia, 53127, Germany
Universitaetsklinikum Freiburg /ID# 275449
RECRUITING

Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
Universitaetsklinikum Hamburg-Eppendorf /ID# 264280
RECRUITING

Hamburg, 20246, Germany
Universitaetsklinikum Schleswig-Holstein - Campus Luebeck /ID# 264284
RECRUITING

Lübeck, Schleswig-Holstein, 23538, Germany
Universitaetsklinikum Tuebingen /ID# 264283
RECRUITING

Tübingen, Baden-Wurttemberg, 72076, Germany
Universitaetsmedizin Goettingen - Georg-August-Universitaet /ID# 264282
RECRUITING

Göttingen, Lower Saxony, 37075, Germany
Universitair Ziekenhuis Leuven /ID# 261302
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium
University General Hospital Attikon /ID# 264914
RECRUITING

Athens, Attica, 12462, Greece

Contact Phone: •••-•••-••••
University General Hospital of Larissa /ID# 264247
RECRUITING

Larissa, 41110, Greece
Wolfe Eye Clinic - West Des Moines /ID# 263270
RECRUITING

West Des Moines, Iowa, 50266, United States
Yitzhak Shamir Medical Center /ID# 275679
RECRUITING

Ẕerifin, Central District, 70300, Israel

Conditions

Explore the condition pages connected to this study.

NEOVASCULAR AGE-RELATED MACULAR DEGENERATION