One-Shot gene therapy could replace monthly eye injections for vision loss

NCT ID NCT05984927

Summary

This early-stage study is testing a one-time gene therapy injection for people with wet age-related macular degeneration (AMD), a leading cause of vision loss in older adults. The goal is to see if this single treatment can safely help control the disease and reduce the need for the frequent anti-VEGF eye injections patients currently require. Researchers will enroll about 20 participants to first check safety and look for early signs that the therapy works.

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Contacts and locations

Locations

  • Cincinnati Eye Institute

    Cincinnati, Ohio, 45242, United States

  • Retina Consultants of Texas

    Bellaire, Texas, 77401, United States

  • Sunnybrook Ophthalmology and Vision Services

    Toronto, Ontario, M4N 3M5, Canada

  • Vancouver Coastal Health Research Institute

    Vancouver, British Columbia, V5Z 3N9, Canada

  • Vitreous Retina Macula Specialists of Toronto

    Toronto, Ontario, M8X 2X3, Canada

Conditions

Explore the condition pages connected to this study.