One-Shot gene therapy tested to fix bleeding disorder
NCT ID NCT03370172
Summary
This early-stage study tested a single intravenous infusion of an experimental gene therapy called BAX 888 in adult men with severe hemophilia A. The main goals were to check for side effects and find a safe and effective dose. Researchers hoped the therapy would help the body produce its own missing clotting factor, potentially reducing or eliminating the need for regular factor VIII injections.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEMOPHILIA A are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
AKH - Medizinische Universität Wien
Vienna, 1090, Austria
-
CHU Rennes - Hopital Pontchaillou
Rennes, Ille Et Vilaine, 35000, France
-
CHU Tours - Hôpital Trousseau
Tours, Indre Et Loire, 37044, France
-
CHU de Nantes Site Hotel Dieu
Nantes, Loire Atlantique, 44093, France
-
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
-
Groupement Hospitalier Est- Hôpital Louis Pradel
Bron, Rhone, 69677, France
-
Gulf States Hemophilia and Thrombophilia Center
Houston, Texas, 77030-4009, United States
-
Hopital Jeanne de Flandre - CHU Lille
Lille, Nord, 59037, France
-
Hospital Clinico Universitario de Salamanca
Salamanca, 37007, Spain
-
Hospital Regional Universitario de Malaga
Málaga, 29010, Spain
-
Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
-
Hospital Universitari i Politecnic La Fe
Valencia, 46026, Spain
-
Hospital Universitario La Paz
Madrid, 28046, Spain
-
Hôpital Bicêtre
Le Kremlin-Bicêtre, Val De Marne, 94275, France
-
Hôpital Morvan
Brest, Finistere, 29609, France
-
Hôpital de la Timone
Marseille, Bouches-du-Rhône, 13385, France
-
Klinikum der Johann Wolfgang Goethe-Universitaet
Frankfurt am Main, Hesse, 60590, Germany
-
Medical University of South Carolina (MUSC)
Charleston, South Carolina, 29425, United States
-
Mount Sinai Medical Center
New York, New York, 10029, United States
-
Orthopaedic Hospital DBA Orthopaedic Hemophilia Treatment Center
Los Angeles, California, 90007, United States
-
Phoenix Childrens Hospital
Phoenix, Arizona, 85016, United States
-
Semmelweis Egyetem
Budapest, 1083, Hungary
-
UC Davis Medical Center
Sacramento, California, 95817, United States
-
Universitaetsklinikum Carl Gustav Carus TU Dresden
Dresden, Saxony, 01307, Germany
-
University of Colorado Hemophilia & Thrombosis Center
Aurora, Colorado, 80045, United States
-
Vivantes Klinikum im Friedrichshain
Berlin, 10249, Germany
Conditions
Explore the condition pages connected to this study.