Gene therapy trial aims to halt vision loss from inherited eye disease
NCT ID NCT06388200
Summary
This Phase 3 study is testing whether a one-time gene therapy called OCU400 can help preserve functional vision in people with retinitis pigmentosa (RP), a genetic disease that causes progressive vision loss. The therapy is injected under the retina. The study has enrolled 140 participants, some with a specific gene mutation (RHO) and others with various RP-causing mutations, to see if the treatment is safe and effective compared to a control group.
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Contacts and locations
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Locations
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Advanced Research, LLC.
Deerfield Beach, Florida, 33064, United States
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Associated Retina Consultants
Phoenix, Arizona, 85020, United States
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Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine
Miami, Florida, 33136, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Calgary Retina Consultants
Calgary, Alberta, T2H OC8, Canada
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Erie Retina Research LLC
Erie, Pennsylvania, 16507, United States
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Gundersen Health System
La Crosse, Wisconsin, 54601, United States
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Research Institute of the McGill University Health Centre
Montreal, Quebec, H2W 1L4, Canada
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Retina Consultants of Texas
Bellaire, Texas, 77401, United States
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Retina Foundation of the Southwest
Dallas, Texas, 75231, United States
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Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
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The University of British Columbia
Vancouver, British Columbia, V5Z 3N9, Canada
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University of Alberta
Edmonton, Alberta, T6G 3E1, Canada
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University of Southern Califormia
La Jolla, California, 92093, United States
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University of Southern California, Roski Eye Insitute
Los Angeles, California, 90033, United States
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Valley Retina Institute
McAllen, Texas, 78503, United States
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Vanderbilt Eye Institute
Nashville, Tennessee, 37232, United States
Conditions
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