Brain surgery trial tests gene therapy to fight Parkinson's

NCT ID NCT06285643

Summary

This study is testing whether a gene therapy delivered directly into the brain can help control symptoms in people with moderate Parkinson's disease. Participants will receive either the real gene therapy or a sham (fake) surgery, and neither they nor the doctors will know which one they got. The main goal is to see if the treatment safely increases the amount of good, symptom-free time people experience over 18 months.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CenExel Rocky Mountain Clinical Research (Neurology)

    RECRUITING

    Englewood, Colorado, 80113, United States

    Contact Phone: •••-•••-••••

  • Charité - Universitätsmedizin Berlin (Surgical)

    ACTIVE_NOT_RECRUITING

    Berlin, Germany

  • Cleveland Clinic Lou Ruvo (Neurology)

    RECRUITING

    Las Vegas, Nevada, 89106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Copernicus Podmiot Leczniczy, Szpital św. Wojciecha (Neurology)

    RECRUITING

    Gdansk, Poland

    Contact Email: •••••@•••••

  • Duke Neurosurgery (Surgical)

    ACTIVE_NOT_RECRUITING

    Durham, North Carolina, 27705, United States

  • Duke University (Neurology)

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emory University (Surgical)

    ACTIVE_NOT_RECRUITING

    Atlanta, Georgia, 30322, United States

  • EvergreenHealth Research Department (Neurology)

    RECRUITING

    Kirkland, Washington, 98034, United States

    Contact Email: •••••@•••••

  • Georgetown University (Neurology)

    RECRUITING

    Washington D.C., District of Columbia, 20057, United States

    Contact Email: •••••@•••••

  • Houston Methodist (Neurology)

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

  • Houston Methodist (Surgical)

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • Loma Linda University (Neurology)

    RECRUITING

    Loma Linda, California, 92354, United States

    Contact Email: •••••@•••••

  • Loma Linda University (Surgical)

    ACTIVE_NOT_RECRUITING

    Loma Linda, California, 92354, United States

  • Massachusetts General Hospital (Neurology)

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

  • Massachusetts General Hospital (Surgical)

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mazowiecki Szpital Bródnowski (Neurology)

    RECRUITING

    Warsaw, Poland

    Contact Email: •••••@•••••

  • Mazowiecki Szpital Bródnowski (Surgical)

    ACTIVE_NOT_RECRUITING

    Warsaw, Poland

  • Michigan State University (Neurology)

    RECRUITING

    East Lansing, Michigan, 48824, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • North Bristol NHS Trust - Southmead Hospital (Neurology)

    RECRUITING

    Bristol, United Kingdom

    Contact Email: •••••@•••••

  • Ohio State University (Surgical)

    ACTIVE_NOT_RECRUITING

    Columbus, Ohio, 43210, United States

  • Parkinson's Disease Treatment Center of Southwest Florida (Neurology)

    ACTIVE_NOT_RECRUITING

    Port Charlotte, Florida, 33980, United States

  • Parkinson's Disease and Movement Disorders Center of Boca Raton (Neurology)

    RECRUITING

    Boca Raton, Florida, 33486, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Philipps-Universität Marburg (Neurology)

    RECRUITING

    Marburg, Germany

    Contact Email: •••••@•••••

  • Quest Research Institute (Neurology)

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

    Contact Email: •••••@•••••

  • Rush University Medical Center (Neurology)

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-••••

  • Samodzielny Publiczny Szpital Kliniczny im. Prof. W. Orłowskiego CMKP (Neurology)

    RECRUITING

    Warsaw, Poland

    Contact Email: •••••@•••••

  • Specjalistyczna Praktyka Lekarska Prof. Grzegorz Opala (Neurology)

    RECRUITING

    Katowice, Poland

    Contact Email: •••••@•••••

  • UCI Alpha Clinic (Neurology)

    RECRUITING

    Irvine, California, 92697, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Wales (Surgical)

    ACTIVE_NOT_RECRUITING

    Cardiff, United Kingdom

  • University of California San Francisco (Neurology)

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

  • University of Kansas Medical Center (Neurology)

    RECRUITING

    Kansas City, Kansas, 66103, United States

    Contact Email: •••••@•••••

  • University of North Carolina (Neurology)

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact Email: •••••@•••••

  • University of Pennsylvania (Neurology)

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of San Francisco (Surgical)

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94143, United States

  • University of Wisconsin (Neurology)

    RECRUITING

    Madison, Wisconsin, 53705, United States

    Contact Email: •••••@•••••

  • Universitätsklinikum Tübingen (Neurology)

    RECRUITING

    Tübingen, Germany

    Contact Email: •••••@•••••

  • Universitätsklinikum Tübingen (Surgical)

    ACTIVE_NOT_RECRUITING

    Tübingen, Germany

  • Universitätsklinikum Würzburg (Neurology)

    RECRUITING

    Würzburg, Germany

    Contact Email: •••••@•••••

  • Vanderbilt University (Neurology)

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.